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It is also a sensitive molecule: investigators handling it pay close attention to handling, storage, and protocol design

Injecting testosterone cypionate has its advantages over the cream, but there are significant safety risks, as well.2 One issue with testosterone cypionate arises from how it causes a spike in testosterone a few days after the injection, followed by a steady decline until your next dose, with doses spaced out every 2-4 weeks.17 That fluctuation can cause mood swings, libido issues, and other side effects